In accordance to the tradition of the Oriental Orthodox Church the Trisagion first occurred during the time when Christ was taken down from the cross. The Angelical hosts from the heavenly realms began to utter from multiple directions: “Holy art Thou O God”, “Holy art Thou Almighty”, and “Holy art Thou Immortal”. Hearing this, those who were gathered at the foot of the cross in awe and fear responded, “Thou who art crucified for us, have mercy on us!”
